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Patients present with any degree of bleeding from a smear on the toilet tissue to severe haemorrhage. Various causes are presented in Figure R1.
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Local causes of bleeding include excoriated skin, anal fissure, a burst perianal haematoma and anal carcinoma. A characteristic pattern of bright bleeding is found with haemorrhoids. It is usually small, non-prolapsing haemorrhoids that bleed.
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Black tarry (melaena) stool indicates bleeding from the upper gastrointestinal tract and is rare distal to the lower ileum.
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Key history Nature of the bleed, including fresh versus altered blood, mixed with faeces and/or mucus, in toilet bowl or on underwear. Quantity of bleeding: slight, moderate or torrential. Associated symptoms (e.g. weight loss, constipation, diarrhoea, pain, weakness, presence of lumps, urgency, unsatisfied defecation, recent change of bowel habit).
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Red flag pointers
Age >50 yrs
Change of bowel habit
Weight loss
Brisk bleeding
Constipation
FH cancer
Haemorrhoids
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General inspection (evidence of anaemia) and vital signs
Abdominal examination, anal inspection, digital rectal examination, proctosigmoidoscopy
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FBE and ESR
Stool M&C
Faecal occult blood
Colonoscopy
Consider abdominal X-ray, CT colonography, angiography, small bowel enema (depending on clinical findings)